Medicinal Chemistry of Neglected and Tropical Diseases

Medicinal Chemistry of Neglected and Tropical Diseases

Advances in the Design and Synthesis of Antimicrobial Agents

Jayaprakash, Venkatesan; Castagnolo, Daniele; OEzkay, Yusuf

Taylor & Francis Ltd

08/2019

380

Dura

Inglês

9781138541245

15 a 20 dias

954

Descrição não disponível.
Key Concepts in Assay Development, Screening and the Properties of Lead and Development Candidate Compounds. The Application of Fragment-based Approaches to the Discovery of Drugs for Neglected Tropical Diseases. Chemical Hybridization Approaches Applied to Natural and Synthetic Compounds for the Discovery of Drugs Active Against Neglected Tropical Diseases. Current Inhibitors of Dengue Virus: An Overview. Overview of Drugs Used Against Zika Virus. Chikungunya Virus Infection: A Review on its Control and Treatment. Recent Advances in Repositioning Non-Antibiotics against Tuberculosis and Other Neglected Tropical Diseases. Prospects of Pre-clinical [6.6.0] Bicyclic Nitrogen Heterocycles in the Treatment of Tuberculosis. Progress in Antimalarial Drug Discovery and Development. Hits and Lead Discovery in the Identification of New Drugs against the Trypanosomatidic Infections. New Chemical Scaffolds to Selectively Target the Trypanothione Metabolism. The Renewal of Interest in Nitroaromatic Drugs: Towards New Anti-Kinetoplastid Agents. New Biological Targets for the Treatment of Leishmaniasis. Curcumin and Neglected Infectious Diseases. An Overview of Helminthiasis: Current State and Future Directions.
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CHIKV Infection;ZIKV RNA;Rational Drug Design;Fragment Molecular Orbital;Medicinal Chemistry;Anti-leishmanial Activity;Chemotherapeutic Agents;Tamil Nadu;Viral proteases;Trypanothione Reductase;Viral fusion inhibitors;Chikungunya Fever;Plasmepsin inhibitors;ADME Property;Antileishmanial Activity;trypanothione synthesis;Extensive SAR Study;neglected tropical diseases treatment;AMR;drug design;Cruzi Amastigotes;Binding Mode;Cruzi Activity;Mtb H37Rv;ZIKV Infection;TR Inhibitor;Crystallographic Complexes;DENV Vaccine;BACTEC 12B Medium;Fragment Screen;anti-TB Activity;CYP Inhibition;PDB Code;Ferric Heme Iron