Textbook of Clinical Trials in Oncology

Textbook of Clinical Trials in Oncology

A Statistical Perspective

Halabi, Susan; Michiels, Stefan

Taylor & Francis Ltd

05/2019

626

Dura

Inglês

9781138083776

15 a 20 dias

1360

Descrição não disponível.
The need for this book. Selection of endpoints. Co-primary Endpoints. Surrogate Endpoints. Innovative Phase I. Phase II. Phase II Biomarker, basket trials. Sample Size for phase III. Multi-Arm trials. Non-inferiority trials. Cure Rate. Design and Analysis of Immunotherapy Trials Data Monitoring Superiorirty and Futility Monitoring. Competing Risks. Missing Data. Multiple Comparison. Biomarker-based clinical trials. Adaptive designs. Trials designs for rare diseases in oncology. Prognostic Models. Validation Approaches. Identification of Predictive Markers. Subgroup Analysis. Statistical Issues in Genomic Studies. Developing and Validation of Signature
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Accelerated Failure Time Model;Semi-parametric Cox Proportional Hazards Models;cancer;Variable Importance Score;competing risks;Promotion Time Cure Model;survival;Interim Analysis;prognostic;Adaptive Enrichment Design;biomarker;Sample Size Calculation;adaptive;Basket Trials;Early Breast Cancer;EORTC QLQ C30;Sample Size Re-estimation;IFN Group;Cumulative Incidence Function;Ich E9;Missing Data;Biomarker Positive Patients;Non-inferiority Trials;Non-inferiority Margin;PD;Multiplicity Adjustment;Log Rank Test;MCM;CRT;Ich E11;True Mtd