Retinoids in Dermatology

1. The background of retinoids. 2. Mechanism of action of vitamin A. 3. Mechanism of action of topical retinoids. 4. Mechanism of action of isotretinoin. 5. Mechanism of action of acitretin. 6. Mechanism of action of bexarotene. 7. Mechanism of action of alitretinoin. 8. Effects of retinoids at the cellular level (differentiation, apaptosis, autophagy, cell cycle regulation, and senescence. 9. Effects of retinoids at the systemic level. 10. New aspects of isotretinoin teratogenicity. 11. Mucocutaneous side effects. 12. Ophthalmologic side effects. 13. Musculoskeletal side effects. 14. Neurologic side effects. 15. Psychiatric side effects. 16. Gastrointestinal side effects. 17. Endocrine and metabolic side effects. 18. Other systemic side effects: Cardiovascular, pulmonary, otolaryngorhinologic, genitourinary, renal, and immunologic. 19. Retinoids in acne. 20. Retinoids in hydradenitis supurativa/acne inversa. 21. Retinoids in rosacea. 22. Retinoids in hair disorders. 23. Retinoids in psoriasis. 24. Retinoids in keratinization disorders. 25. Retinoids in antiaging therapy. 26. Retinoids in other skin diseases. 27. Retinoids in lymphoma. 28.Retinoids in cutaneous chemoprophylaxis. 29. Guide to good clinical practice for vulnerable populations (infancy, childhood, fertile period, elderly). 30. Retinoids and concomitant surgery. 31. Retinoids and concomitant aesthetic procedures. 32. Laboratory and clinical follow-up. 33. Teratogenicity and registry programs. 34. Management of side effects. 35. Future and novel unexplored indications of retinoids.

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• Farmacologia
• Dermatologia
• Cirurgia plástica e reconstructiva

cutaneous pharmacology;autophagy regulation;cell differentiation mechanisms;apoptosis pathways;adverse drug reactions;vulnerable patient management;retinoid therapy for skin disorders