Non-Clinical Vascular Infusion Technology, Volume I
-10%
portes grátis
Non-Clinical Vascular Infusion Technology, Volume I
The Science
Healing, Guy; Green, Owen P.
Taylor & Francis Ltd
11/2018
215
Mole
Inglês
9781138382169
15 a 20 dias
400
Descrição não disponível.
Body Fluid Dynamics. Introduction. Composition and units of measurement. Compartmentalization and Distribution. Movement between Compartments/Exchange. Body Fluid Homeostasis. Summary. References. Physico-Chemical Factors. Introduction. Osmolality. Acid-Base Balance. Viscosity. Surface Tension. Diffusion. Summary of Infusion Forces. References. Vascular Infusion Dynamics. Essential physiology. Intravenous Delivery Rates and Volumes. References. Formulation Considerations. Introduction. Formulation selection strategy. Study design and species/strain. The properties of the compound. Strategies for dealing with poor solubility. Unwanted formulation effects. Excipient toxicity. Strategies for dealing with injection site reactions and haemolysis. Strategies for dealing with poor stability. Sterility. Conclusion. References. Prestudy analytical assessments: Equipment compatibility. Stability of the formulation with the formulation storage vessel. Compatibility. Choice of material. References. Haemocompatibility. Introduction. Objectives. Methods of assessing haemocompatibility. Discussion. Conclusion. References. Annex: Common excipients and vehicles.
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Cremophor EL;Vascular Infusion;Infusion delivery;Dose Volume;Aqueous Sodium Chloride;Formulation science;Acid Base Disturbance;Non-clinical models;Reduced Drug Delivery;Anion Gap;Injection Site Reactions;Metabolic Alkalosis;Freezing Point Depression;Implantable Pump;Venous Blood Vessels;Laboratory Animal Species;Respiratory Acidosis;IACUC;Compatibility Trial;PVC Bag;Respiratory Alkalosis;Saline Flush;Impermeant Solutes;Body Fluid Homeostasis;Infusion System;Blood pH;Paclitaxel Injections;Intravenous Delivery
Body Fluid Dynamics. Introduction. Composition and units of measurement. Compartmentalization and Distribution. Movement between Compartments/Exchange. Body Fluid Homeostasis. Summary. References. Physico-Chemical Factors. Introduction. Osmolality. Acid-Base Balance. Viscosity. Surface Tension. Diffusion. Summary of Infusion Forces. References. Vascular Infusion Dynamics. Essential physiology. Intravenous Delivery Rates and Volumes. References. Formulation Considerations. Introduction. Formulation selection strategy. Study design and species/strain. The properties of the compound. Strategies for dealing with poor solubility. Unwanted formulation effects. Excipient toxicity. Strategies for dealing with injection site reactions and haemolysis. Strategies for dealing with poor stability. Sterility. Conclusion. References. Prestudy analytical assessments: Equipment compatibility. Stability of the formulation with the formulation storage vessel. Compatibility. Choice of material. References. Haemocompatibility. Introduction. Objectives. Methods of assessing haemocompatibility. Discussion. Conclusion. References. Annex: Common excipients and vehicles.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Cremophor EL;Vascular Infusion;Infusion delivery;Dose Volume;Aqueous Sodium Chloride;Formulation science;Acid Base Disturbance;Non-clinical models;Reduced Drug Delivery;Anion Gap;Injection Site Reactions;Metabolic Alkalosis;Freezing Point Depression;Implantable Pump;Venous Blood Vessels;Laboratory Animal Species;Respiratory Acidosis;IACUC;Compatibility Trial;PVC Bag;Respiratory Alkalosis;Saline Flush;Impermeant Solutes;Body Fluid Homeostasis;Infusion System;Blood pH;Paclitaxel Injections;Intravenous Delivery
